Pulmonary vasodilator responses to adrenomedullin are reduced by NOS inhibitors in rats but not in cats.

Abstract

Responses to and the mechanism of action of adrenomedullin (ADM), the carboxy-terminal fragments of ADM, and calcitonin gene-related peptide (CGRP), a structurally related peptide, were investigated in the pulmonary vascular bed of the rat. Under conditions of elevated tone and controlled pulmonary blood flow in the isolated blood-perfused rat lung… (More)

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@article{Nossaman1996PulmonaryVR, title={Pulmonary vasodilator responses to adrenomedullin are reduced by NOS inhibitors in rats but not in cats.}, author={Bobby Dean Nossaman and Chong-hui Feng and Alan David Kaye and Bracken J Dewitt and David H. Coy and Wilmon Murphy and Philip J. Kadowitz}, journal={The American journal of physiology}, year={1996}, volume={270 5 Pt 1}, pages={L782-9} }