Pulmonary transplantation: the role of brain death in donor lung injury.

@article{Avlonitis2003PulmonaryTT,
  title={Pulmonary transplantation: the role of brain death in donor lung injury.},
  author={Vassilios Spiridon C. Avlonitis and Andrew J Fisher and John Andrew Kirby and John Henry Dark},
  journal={Transplantation},
  year={2003},
  volume={75 12},
  pages={1928-33}
}
The paucity of suitable lung donors and the high early mortality as the result of primary graft failure remain major challenges in pulmonary transplantation. There is evidence that the lung is injured in the donor by the process of brain death and often is made unusable or fails posttransplantation after amplification of the injury by the process of ischemia-reperfusion. An understanding of the mechanism of donor lung injury could lead to the development of new treatment strategies for the… CONTINUE READING

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