Pulmonary surfactants and their role in pathophysiology of lung disorders.

  title={Pulmonary surfactants and their role in pathophysiology of lung disorders.},
  author={Aparna Akella and Shripad Bhimarao Deshpande},
  journal={Indian journal of experimental biology},
  volume={51 1},
Surfactant is an agent that decreases the surface tension between two media. The surface tension between gaseous-aqueous interphase in the lungs is decreased by the presence of a thin layer of fluid known as pulmonary surfactant. The pulmonary surfactant is produced by the alveolar type-II (AT-II) cells of the lungs. It is essential for efficient exchange of gases and for maintaining the structural integrity of alveoli. Surfactant is a secretory product, composed of lipids and proteins… CONTINUE READING
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