Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro

@inproceedings{Gasser2011PulmonarySC,
  title={Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro},
  author={Michael Gasser and Peter Wick and Martin J. D. Clift and Fabian Blank and Liliane Diener and Bing Yan and Peter Gehr and Harald F Krug and Barbara Rothen-Rutishauser},
  booktitle={Particle and Fibre Toxicology},
  year={2011}
}
Increasing concern has been expressed regarding the potential adverse health effects that may be associated with human exposure to inhaled multi-walled carbon nanotubes (MWCNTs). Thus it is imperative that an understanding as to the underlying mechanisms and the identification of the key factors involved in adverse effects are gained. In the alveoli, MWCNTs first interact with the pulmonary surfactant. At this interface, proteins and lipids of the pulmonary surfactant bind to MWCNTs, affecting… CONTINUE READING