Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe.

@article{Driehuys2009PulmonaryPA,
  title={Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe.},
  author={Bastiaan Driehuys and Harald E. M{\"o}ller and Zackary I. Cleveland and James R Pollaro and Laurence W. Hedlund},
  journal={Radiology},
  year={2009},
  volume={252 2},
  pages={
          386-93
        }
}
PURPOSE To develop and demonstrate a method for regional evaluation of pulmonary perfusion and gas exchange based on intravenous injection of hyperpolarized xenon 129 ((129)Xe) and subsequent magnetic resonance (MR) imaging of the gas-phase (129)Xe emerging in the alveolar airspaces. MATERIALS AND METHODS Five Fischer 344 rats that weighed 200-425 g were prepared for imaging according to an institutional animal care and use committee-approved protocol. Rats were ventilated, and a 3-F catheter… CONTINUE READING

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  • Journal of magnetic resonance
  • 2016
VIEW 1 EXCERPT
CITES METHODS

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

3He MRI in mouse models of asthma.

  • Magnetic resonance in medicine
  • 2007
VIEW 1 EXCERPT

Lung MRI for experimental drug research.

  • European journal of radiology
  • 2007
VIEW 1 EXCERPT

Imaging alveolar-capillary gas transfer using hyperpolarized 129Xe MRI.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2006
VIEW 3 EXCERPTS

MR imaging of pulmonary perfusion and gas exchange by intravenous injection of hyperpolarized 129Xe [abstr

B Driehuys, HE Moeller, J Pollaro, LW. Hedlund
  • Proceedings of the Fourteenth Meeting of the International Society for Magnetic Resonance in Medicine. Berkeley,
  • 2006
VIEW 1 EXCERPT

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