Pulmonary performance of elderly normal subjects and subjects with chronic obstructive pulmonary disease exposed to 0.3 ppm nitrogen dioxide.

@article{Morrow1992PulmonaryPO,
  title={Pulmonary performance of elderly normal subjects and subjects with chronic obstructive pulmonary disease exposed to 0.3 ppm nitrogen dioxide.},
  author={Paul E. Morrow and Mark J. Utell and Michael Anthony Bauer and Anthony Smeglin and Mark W. Frampton and Christopher Cox and Donna M. Speers and F. Gibb},
  journal={The American review of respiratory disease},
  year={1992},
  volume={145 2 Pt 1},
  pages={291-300}
}
Symptoms and changes in pulmonary function of subjects with chronic obstructive pulmonary disease (COPD) and elderly normal subjects, induced by a 4-h exposure to 0.3 ppm NO2, were investigated using a double-blind, crossover design with purified air. The 5-day experimental protocol required approximately 2 wk with at least a 5-day separation between randomized 4-h exposures to either NO2 or air which included several periods of exercise. Over a 2-yr period, COPD subjects, all with a history of… CONTINUE READING