Pulmonary outcome at 1 year corrected age in premature infants treated at birth with recombinant human CuZn superoxide dismutase.

@article{Davis2003PulmonaryOA,
  title={Pulmonary outcome at 1 year corrected age in premature infants treated at birth with recombinant human CuZn superoxide dismutase.},
  author={Jonathan M. V. Davis and Richard B Parad and Theresa M Michele and Elizabeth N. Allred and Anita Price and Warren N Rosenfeld},
  journal={Pediatrics},
  year={2003},
  volume={111 3},
  pages={469-76}
}
OBJECTIVE To examine whether treatment of premature infants with intratracheal recombinant human CuZn superoxide dismutase (r-h CuZnSOD) reduces bronchopulmonary dysplasia and improves pulmonary outcome at 1 year corrected age. DESIGN Three hundred two premature infants (600-1200 g birth weight) treated with exogenous surfactant at birth for respiratory distress syndrome were randomized to receive either intratracheal r-h CuZnSOD (5 mg/kg in 2 mL/kg saline) or placebo every 48 hours (as long… CONTINUE READING

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