Pulmonary neuroendocrine cells in nitrofen-induced diaphragmatic hernia and the effect of prenatal glucocorticoids

@article{Gosney1999PulmonaryNC,
  title={Pulmonary neuroendocrine cells in nitrofen-induced diaphragmatic hernia and the effect of prenatal glucocorticoids},
  author={John R. Gosney and Bruce Obi Okoye and David A. J. Lloyd and Paul D Losty},
  journal={Pediatric Surgery International},
  year={1999},
  volume={15},
  pages={180-183}
}
The high mortality associated with congenital diaphragmatic hernia (CDH) is due to pulmonary hypoplasia and hypertension, structural and functional abnormalities which can to some extent be ameliorated by prenatal administration of glucocorticoids. In the hypoplastic, hypertensive lungs of neonatal rats in which CDH has been induced by nitrofen, those pulmonary neuroendocrine cells (PNCs) containing calcitonin gene-related peptide (CGRP) increase in number, and it has been suggested that this… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 19 REFERENCES

Similar Papers

Loading similar papers…