Pulmonary microembolization in experimental aortic surgery.

  title={Pulmonary microembolization in experimental aortic surgery.},
  author={Keith R Poskitt and Jason T. Irwin and Ian F Lane and Sadettin Karacagil and Charles C. N. McCollum},
  journal={The British journal of surgery},
  volume={75 12},
Pulmonary dysfunction frequently follows major surgery and has many features identical to "shock lung'. A porcine model of aortic surgery is described in which 111In-labelled platelet kinetics were related to subsequent pulmonary function. In 14 pigs, standardized aortic surgery resulted in reproducible shock and a 50 per cent mortality at 3 days. Cardiac output fell from 2.3 +/- 0.2 to 1.0 +/- 0.1 litres min-1 following removal of the aortic clamp and mean platelet and leucocyte counts fell… CONTINUE READING