Pulmonary mechanics during the ventilatory response to hypoxemia in the newborn monkey.

@article{Laframboise1983PulmonaryMD,
  title={Pulmonary mechanics during the ventilatory response to hypoxemia in the newborn monkey.},
  author={William A Laframboise and Robert D. Guthrie and Thomas Standaert and David E Woodrum},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  year={1983},
  volume={55 3},
  pages={1008-14}
}
Dynamic lung compliance (CL), inspiratory pulmonary resistance (RL), and functional residual capacity (FRC) were measured in 10 unanesthetized 48 h-old newborn monkeys and seven 21-day-old infant monkeys during acute exposures to an equivalent level of hypoxemia. End-expiratory airway occlusions were performed and the pressure developed by 200 ms (P0.2) was utilized as an index of central respiratory drive. P0.2 demonstrated a sustained increase throughout the period of hypoxemia on day 2… CONTINUE READING