Pulmonary macrophages are involved in reperfusion injury after lung transplantation.

  title={Pulmonary macrophages are involved in reperfusion injury after lung transplantation.},
  author={Steven M Fiser and Curtis G. Tribble and Stewart M Long and Aditya K. Kaza and John A. Kern and Irving L. Kron},
  journal={The Annals of thoracic surgery},
  volume={71 4},
  pages={1134-8; discussion 1138-9}
BACKGROUND Reperfusion injury is a perplexing cause of early graft failure after lung transplantation. Although recipient neutrophils are thought to have a role in the development of reperfusion injury, some researchers have shown that neutrophils are not involved in its earliest phase. Intrinsic donor pulmonary macrophages may be responsible for this early phase of injury. Using the macrophage inhibitor gadolinium chloride, we attempted to investigate the role of pulmonary macrophages in… CONTINUE READING


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