Pulmonary inflammation induced by repeated inhalations of beta(1,3)-D-glucan and endotoxin.

@article{Fogelmark1994PulmonaryII,
  title={Pulmonary inflammation induced by repeated inhalations of beta(1,3)-D-glucan and endotoxin.},
  author={Birgitta Fogelmark and Margareta Sj{\"o}strand and R. Lynn Rylander},
  journal={International journal of experimental pathology},
  year={1994},
  volume={75 2},
  pages={
          85-90
        }
}
In an animal model of hypersensitivity pneumonitis (HP) guinea-pigs were exposed for 5 weeks to an aerosol of bacterial endotoxin, beta(1,3)-D-glucan (curdlan) or a combination. Exposure to endotoxin or curdlan showed only small changes in inflammatory cells in airways or the lung wall, histologically or in terms of enzyme secretion from alveolar macrophages. When the two agents were given together, a histology resembling HP was seen with alveolar infiltrates and early granulomas. Inflammatory… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 58 CITATIONS, ESTIMATED 97% COVERAGE

The role of inhaled endotoxin in the aetiopathogenesis of equine heaves

VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

(1-->3)-beta-D-glucan and endotoxin modulate immune response to inhaled allergen.

  • Mediators of inflammation
  • 1998
VIEW 6 EXCERPTS
CITES RESULTS, BACKGROUND & METHODS
HIGHLY INFLUENCED

Pulmonary cell infiltration after chronic exposure to (1→3)--D-glucan and cigarette smoke

  • Inflammation Research
  • 1997
VIEW 6 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1996
2018

CITATION STATISTICS

  • 5 Highly Influenced Citations

Similar Papers