Pulmonary hypertension in heart failure with preserved ejection fraction.

  title={Pulmonary hypertension in heart failure with preserved ejection fraction.},
  author={Marco Guazzi and Mardi Gomberg-Maitland and Ross Arena},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  volume={34 3},
In heart failure with preserved ejection fraction (HFpEF), an entity that remains challenging and difficult to treat, the development of pulmonary hypertension (PH), via an increase in left atrial pressure, is the direct consequence of reduced relaxation and enhanced stiffness of the left ventricle and is now viewed as an important contributor to clinical worsening and increased mortality. PH becomes a relevant clinical phenotype in approximately 50% of patients with HFpEF and represents a true… CONTINUE READING
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