Pulmonary hypertension, hypoxemia, and hypercapnia in obstructive sleep apnea patients.

@article{Krieger1989PulmonaryHH,
  title={Pulmonary hypertension, hypoxemia, and hypercapnia in obstructive sleep apnea patients.},
  author={J. B. Krieger and Emilia Sforza and M. Apprill and Eliane Lampert and Emmanuel Weitzenblum and J Ratomaharo},
  journal={Chest},
  year={1989},
  volume={96 4},
  pages={729-37}
}
To define the parameters of respiratory insufficiency in OSA, 114 consecutive patients (108 men, six women) were prospectively studied. In addition to standard polysomnography, they underwent pulmonary function tests, right heart catheterization, and ventilatory response tests to hypercapnia. Nineteen patients (19 percent) had a resting PAP greater than or equal to 20 mm Hg. Multiple regression analysis showed that FEV1 and PaO2 (both with a negative coefficient) and PaCO2 (with a positive… CONTINUE READING
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Sleep apnea syndrome : ventilatory and mouth occlusion pressure responses to progressive hypoxia and hypercapnia

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lime course of change in ventilatory response to CO2 with long-term CPAP therapy for obstructive sleep apnea

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