Pulmonary hemodynamics at birth: effect of acute cyclooxygenase inhibition in lambs.

@article{Davidson1988PulmonaryHA,
  title={Pulmonary hemodynamics at birth: effect of acute cyclooxygenase inhibition in lambs.},
  author={Dennis Davidson},
  journal={Journal of applied physiology},
  year={1988},
  volume={64 4},
  pages={1676-82}
}
The effect of acute cyclooxygenase (CYO) inhibition on the cardiopulmonary adjustments at birth was examined in chronically instrumented, unanesthetized, term lambs before, during, and after cesarean section (spontaneous respiration). One of three infusions was started 20 min before birth: saline control (C, n = 6), indomethacin (I, n = 6), or meclofenamate (M, n = 3). The stable metabolite of prostacyclin, plasma 6-ketoprostaglandin F1 alpha (6-keto-PGF1 alpha, aorta), was measured by… CONTINUE READING

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