Pulmonary epithelial lining fluid concentrations after use of systemic amphotericin B lipid formulations.

@article{Weiler2009PulmonaryEL,
  title={Pulmonary epithelial lining fluid concentrations after use of systemic amphotericin B lipid formulations.},
  author={Stefan Weiler and Gerda Falkensammer and Angelika Hammerer-Lercher and Markus Anliker and Helene Vogelsinger and Michael Joannidis and Stefan Dunzendorfer and Markus Chagas Stein and Romuald Bellmann},
  journal={Antimicrobial agents and chemotherapy},
  year={2009},
  volume={53 11},
  pages={
          4934-7
        }
}
Amphotericin B (AMB) concentrations were determined in pulmonary epithelial lining fluid (ELF) of 44 critically ill patients, who were receiving treatment with liposomal AMB (LAMB) (n = 11), AMB colloidal dispersion (ABCD) (n = 28), or AMB lipid complex (ABLC) (n = 5). Mean AMB levels (+/- standard errors of the means) in ELF amounted to 1.60 +/- 0.58, 0.38 +/- 0.07, and 1.29 +/- 0.71 microg/ml in LAMB-, ABCD-, and ABLC-treated patients, respectively (differences are not significant). 

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