Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.

@article{Varani1985PulmonaryEC,
  title={Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.},
  author={James Varani and Suzanne E. G. Fligiel and Gerd O. Till and Robin G. Kunkel and Una S. Ryan and Peter A Ward},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1985},
  volume={53 6},
  pages={656-63}
}
Human blood neutrophils stimulated by a variety of agents were shown to have cytotoxic effects on bovine pulmonary artery endothelial cells. Effective agonists included immune complexes, opsonized zymosan and 12-O-tetradecanoyl phorbol acetate. Unstimulated human neutrophils and neutrophils stimulated with N-formyl-methionyl-leucyl-phenylalanine or with… CONTINUE READING