Pulmonary endothelial cell activation during experimental acute kidney injury.

@article{Feltes2011PulmonaryEC,
  title={Pulmonary endothelial cell activation during experimental acute kidney injury.},
  author={Carolyn Feltes and Heitham T. Hassoun and Mihaela L. Lie and Chris Cheadle and Hamid Rabb},
  journal={Shock},
  year={2011},
  volume={36 2},
  pages={170-6}
}
Acute kidney injury (AKI) leads to increased lung microvascular permeability, leukocyte infiltration, and upregulation of soluble inflammatory proteins in rodents. Most work investigating connections between AKI and pulmonary dysfunction, however, has focused on characterizing whole lung tissue changes associated with AKI. Studies at the cellular level are essential to understanding the molecular basis of lung changes during AKI. Given that the pulmonary microvascular barrier is functionally… CONTINUE READING
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