Pulmonary endodermal tumor resembling fetal lung. The optically clear nucleus is rich in biotin.

@article{Nakatani1994PulmonaryET,
  title={Pulmonary endodermal tumor resembling fetal lung. The optically clear nucleus is rich in biotin.},
  author={Yukio Nakatani and Hitoshi Kitamura and Yoshiaki Inayama and Nobuo Ogawa},
  journal={The American journal of surgical pathology},
  year={1994},
  volume={18 6},
  pages={637-42}
}
Pulmonary endodermal tumor resembling fetal lung (PET) is a rare pulmonary neoplasm that may represent a distinctive form of pulmonary blastoma lacking the sarcomatous component. A peculiar histologic feature of PET is the presence in the morular area of optically clear nuclei (OCN), which commonly show false-positive immunostaining by the avidin-biotin peroxidase complex (ABC) method. Because recent studies have shown that the nuclei of an identical change seen in endometrioid adenocarcinoma… CONTINUE READING

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