Pulmonary embolism in pregnancy

@article{Bourjeily2010PulmonaryEI,
  title={Pulmonary embolism in pregnancy},
  author={Ghada Bourjeily and Michael J. Paidas and Hanan Khalil and Karen Rosene-Montella and Marc Alan Rodger},
  journal={The Lancet},
  year={2010},
  volume={375},
  pages={500-512}
}
Pulmonary embolism (PE) is the leading cause of maternal mortality in the developed world. Mortality from PE in pregnancy might be related to challenges in targeting the right population for prevention, ensuring that diagnosis is suspected and adequately investigated, and initiating timely and best possible treatment of this disease. Pregnancy is an example of Virchow's triad: hypercoagulability, venous stasis, and vascular damage; together these factors lead to an increased incidence of venous… Expand
Pulmonary embolism in pregnancy
TLDR
The main purpose of the present review article was to emphasize the most recent findings and recommendations in diagnostic strategies, discussing thrombophilic risk evaluation, as well as risks and benefits of various diagnostic techniques for both mother and fetus. Expand
Pregnancy and Pulmonary Embolism.
TLDR
During the peripartum period, women should be risk stratified and preventive measures should be initiated based on their risk, and diagnostic tests and treatment strategies commonly used in VTE differ in pregnancy. Expand
[Diagnostic and therapeutic dilemmas in pregnant woman with pulmonary embolism].
TLDR
A case of a 27-year-old pregnant woman with high-risk PE is presented to present to improve clinical assessment of Pulmonary embolism. Expand
Thrombolysis for massive pulmonary embolism in pregnancy: a case report.
Diagnosis and Management of Pulmonary Embolism in Pregnancy
TLDR
In pregnant women who undergo catastrophic and refractory respiratory or hemodynamic collapse unresponsive to typical critical care support, extracorporeal membrane oxygenation (ECMO) can be considered. Expand
Peripartum pulmonary embolism: Anesthetic and surgical considerations
TLDR
Computerized tomographic pulmonary angiography has a high specificity and sensitivity in comparison to ventilation/perfusion scan for diagnosis of peripartum pulmonary embolism (PPE), it has a lower fetal radiation exposure and aids in arriving at an alternative diagnosis, if PPE is absent. Expand
Peripartum pulmonary embolism.
Pregnancy is an example of Virchow's triad predisposing to the development of venous thromboembolism (VTE). Specific risk factors for antepartum and postpartum VTE have been identified. The diagnosisExpand
Pregnancy and venous thromboembolism.
TLDR
There is a need for methodologically strong studies in pregnant women, especially with respect to risk stratification, optimal heparin doses, usefulness of anti-FXa levels and their correlation with clinical outcomes, and correct management of anticoagulation during delivery. Expand
Investigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature.
TLDR
This comprehensive review examines the literature and evidence for the investigation and diagnostic imaging of suspected pulmonary embolism during pregnancy with CTPA and V/Q with a focus on diagnostic accuracy and yield, radiation dose exposure (maternal-foetal) and protocol modifications. Expand
Pulmonary embolism in pregnancy: a diagnostic dilemma
TLDR
This review is focused on various diagnostic options and risks of radiation to the fetus and mother from radiation-based procedures. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 148 REFERENCES
Massive pulmonary embolism during pregnancy successfully treated with recombinant tissue plasminogen activator: a case report and review of treatment options.
TLDR
Women are at increased risk for DVT and PE during pregnancy for several reasons, and women with a history of thrombotic complications during pregnancy have an increased prevalence of genetic mutations related to coagulation. Expand
Diagnosis of pulmonary embolism.
TLDR
In unstable patients with suspected pulmonary embolism, echocardiography should be the initial test, and in patients with a contraindication to CT, lower limb venous ultrasonography and ventilation-perfusion scintigraphy remain valid options. Expand
Risk of fatal pulmonary embolism in patients with treated venous thromboembolism.
TLDR
Among patients with symptomatic PE or DVT who are treated with anticoagulants for 3 months, fatal PE is rare during and following antICOagulant therapy. Expand
Epidemiological observations of thrombo‐embolic disease during pregnancy and in the puerperium, in 56,022 women
TLDR
Puerperal TE was influenced by age, mode of delivery, hypertension and prophylactic anticoagulant therapy, but TE during pregnancy was not noticeably correlated with age and hypertension. Expand
Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period.
TLDR
There is insufficient evidence on which to base recommendations for thromboprophylaxis during pregnancy and the early postnatal period, and large scale randomised trials of currently-used interventions should be conducted. Expand
Suspected pulmonary embolism in pregnancy: clinical presentation, results of lung scanning, and subsequent maternal and pediatric outcomes.
TLDR
The prevalence of high-probability VQ scans in pregnant women with suspected PE and probable PE is very low and holding anticoagulation therapy following a normal or nondiagnostic VQ scan is probably safe. Expand
Venous thromboembolism during pregnancy or postpartum: findings from the RIETE Registry.
TLDR
Comparing the clinical characteristics and outcome for all enrolled pregnant and postpartum women with acute VTE, and all non-pregnant women in the same age range, suggests that thromboprophylaxis should start in the first trimester. Expand
Massive Pulmonary Embolism in Pregnancy Treated With Tissue Plasminogen Activator
TLDR
The successful thrombolysis with t-PA of a massive, life-threatening pulmonary embolism without complications followed by a term delivery is described. Expand
Risk factors for pregnancy associated venous thromboembolism.
TLDR
It is estimated that the thrombotic risk for a woman during pregnancy or the puerperium with the defect is approximately 1 in 400-500, which would not lend support to the idea of random screening for the factor V(Leiden) mutation in early pregnancy. Expand
Use of inferior vena cava filters in thromboembolic disease during labor: Case report with a literature review
  • P. Jamjute, N. Reed, D. Hinwood
  • Medicine
  • The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2006
TLDR
In this case, a patient diagnosed as having a deep vein thrombosis was started on anticoagulant therapy and went into labor and an IVC filter was inserted due to the risk of pulmonary embolism, which was managed successfully during labor and postpartum period. Expand
...
1
2
3
4
5
...