Pulmonary embolism associated with tranexamic acid in severe acquired haemophilia.

@article{Taparia2002PulmonaryEA,
  title={Pulmonary embolism associated with tranexamic acid in severe acquired haemophilia.},
  author={Minakshi Taparia and Frank T Cordingley and Michael F. Leahy},
  journal={European journal of haematology},
  year={2002},
  volume={68 5},
  pages={307-9}
}
Tranexamic acid (an antifibrinolytic agent) is of proven benefit in the treatment of bleeding in patients with congenital and acquired coagulation disorders. We report the case of a patient with an acquired Factor VIII inhibitor, who was on a prophylactic dose of tranexamic acid because of recurrent bleeding episodes and developed a pulmonary embolism. Although studies using tranexamic acid have not shown a definite increased risk for the development of venous thrombosis, this is the likely… CONTINUE READING