Pulmonary effects of acute prenatal asphyxia in ventilated premature lambs.

@article{Berry1988PulmonaryEO,
  title={Pulmonary effects of acute prenatal asphyxia in ventilated premature lambs.},
  author={David D Berry and Alan Hall Jobe and Machiko Ikegami and Steven R Seidner and Andrea Pettenazzo and Tarek Elkady},
  journal={Journal of applied physiology},
  year={1988},
  volume={65 1},
  pages={
          26-33
        }
}
The effect of profound repetitive prenatal asphyxial insults on the cardiopulmonary function of premature ventilated lambs was studied. Twenty-nine fetal lambs (approximately 138 days gestational age) were exteriorized. In 16 of these lambs, the umbilical cord was occluded for 4 min then released for 10 min. This asphyxial episode was repeated until the arterial pH was approximately 7.00, and the mean arterial blood pressure was less than 40 mmHg and falling. The 13 control lambs were simply… CONTINUE READING