Pulmonary distribution and kinetics of inhaled [11C]triamcinolone acetonide.

  title={Pulmonary distribution and kinetics of inhaled [11C]triamcinolone acetonide.},
  author={Marc S. Berridge and Zhenghong Lee and Donald L. Heald},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={41 10},
UNLABELLED Triamcinolone acetonide (TAA) is an anti-inflammatory steroid used for topical treatment of allergic rhinitis and asthma. Drug deposition onto target tissues is an important parameter, so methods for accurate deposition measurement are needed. Lung deposition is especially problematic to measure because of the large field of view and low relative drug penetration. Our main objective was to use PET to measure the deposition and postdeposition kinetics of TAA in the lung after… CONTINUE READING


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