Pulmonary barotrauma in congenital diaphragmatic hernia: a clinicopathological correlation.

@article{Sakurai1999PulmonaryBI,
  title={Pulmonary barotrauma in congenital diaphragmatic hernia: a clinicopathological correlation.},
  author={Yasuhisa Sakurai and Kenneth S Azarow and Ernest Cutz and Antonio Messineo and Russell K. Pearl and Desmond G Bohn},
  journal={Journal of pediatric surgery},
  year={1999},
  volume={34 12},
  pages={1813-7}
}
BACKGROUND/PURPOSE The high mortality rate in congenital diaphragmatic hernia (CDH) has been ascribed to pulmonary hypoplasia and persistent pulmonary hypertension of the newborn (PPHN). One of the principal treatment strategies has been the use of hyperventilation to reverse ductal shunting, but the wisdom of this approach is being questioned because of parenchymal lung injury from high inflation pressures. The authors hypothesize that the use of hyperventilation to reverse or prevent ductal… CONTINUE READING

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