Pulmonary aspiration syndromes

  title={Pulmonary aspiration syndromes},
  author={Paul Ellis Marik},
  journal={Current Opinion in Pulmonary Medicine},
  • P. Marik
  • Published 1 May 2011
  • Medicine
  • Current Opinion in Pulmonary Medicine
Purpose of review Pulmonary aspiration syndromes are a common cause of morbidity and mortality. These syndromes are often misdiagnosed and their management is frequently suboptimal. This paper reviews the clinical features and management of the most common aspiration syndromes. Recent findings Pulmonary aspiration syndromes refer to a group of pulmonary diseases resulting from aspiration of foreign material into the lung. The type of syndrome depends on the quantity and nature of the aspirated… 

Aspiration-related pulmonary syndromes.

The broadening spectrum of aspiration-related pulmonary syndromes is discussed with a focus on presenting features and diagnostic aspects.

Aspiration-Related Lung Diseases

The different types of aspiration lung diseases are reviewed, focusing on their imaging features and differential diagnosis.

Clinical Significance of Aspiration Pneumonia and Diffuse Aspiration Bronchiolitis in the Elderly

Drugs that improve the swallowing reflex, vaccinations and oral health care management are effective in preventing aspiration pneumonia; however, percutaneous endoscopic gastrostomy is not recommended for the purpose of preventing aspirationneumonia.

Solitary lung masses due to occult aspiration.

Aspiration-Related Deaths in 57 Consecutive Patients: Autopsy Study

Asspiration-related deaths occur most commonly in the elderly with identifiable risks and presenting bilateral pulmonary infiltrates and one-third of these aspiration-related pulmonary syndromes were clinically unsuspected at the time of death.

Aspiration Pneumonia in the Geriatric Population

This review seeks to look at aspiration pneumonia focusing on oropharyngeal dysphagia, the microbiology of aspiration pneumonia and the palliative care aspects.

New perspectives in aspiration community acquired Pneumonia

A broad literature review using the MeSH heading in PubMed/MEDLINE of ‘aspiration pneumonia’ from January 1970 to July 2019 found that further research is needed to determine the role of the microbiome with aspiration pneumonia and patient risk factors.

Characteristics and outcomes of patients hospitalized following pulmonary aspiration.

Aspiration was more common in men with alcohol abuse history and a lower Glasgow Coma Scale who were admitted from a nursing home and is independently associated with a significant increase in the risk for ARDS as well as morbidity and mortality.

Aspiration Pneumonitis with Nasal Liquorrhea. Literature Review

Based on the analysis of the literature, aspiration pneumonitis is a rare complication of nasal liquorrhea and to eliminate the cause of aspiration is first of all necessary to perform plastic surgery of the skull base defect in the absence of contraindications from the side of anesthetic aid.



Aspiration Pneumonitis and Aspiration Pneumonia

Aspiration pneumonitis (Mendelson's syndrome), whereas aspiration pneumonia is an infectious process caused by the inhalation of oropharyngeal secretions that are colonized by pathogenic bacteria, are distinct clinical entities.

Importance of diffuse aspiration bronchiolitis caused by chronic occult aspiration in the elderly.

The importance of recognizing DAB and differentiating DAB from pulmonary diseases associated with bronchospasm in the elderly, in particular, late-onset asthma and DPB is emphasized, in view of possible therapeutic intervention.

Diffuse bronchiolar disease due to chronic occult aspiration.

Diffuse bronchiolar disease likely represents an underrecognized form of aspiration-related lung disease and may occur in relatively young Individuals without symptoms suggestive of recurrent aspiration.

Clinical Significance of Pulmonary Aspiration during the Perioperative Period

This study suggests that patients with clinically apparent aspiration who do not develop symptoms within 2 h are unlikely to have respiratory sequelae.

The role of anaerobes in patients with ventilator-associated pneumonia and aspiration pneumonia: a prospective study.

The use of antibiotics with anaerobic coverage may not be necessary in patients with suspected VAP and AP, and penicillin G and clindamycin mayNot be the antibiotics of choice in Patients with AP.

High incidence of silent aspiration in elderly patients with community-acquired pneumonia.

Scanning of the thorax demonstrated that 71% of patients aspirated, whereas aspiration was observed in only 10% of control subjects, which may indicate an important role of silent aspiration in the development of community-acquired pneumonia in the elderly.

The aspiration of stomach contents into the lungs during obstetric anesthesia.

A survey of New York Lying-In Hospital records of patients that aspirated gastric contents during obstetric anesthesia revealed the following different diagnoses: suffocation, massive atelectasis, partial at electasis, disc atelectases, pulmonary infarct, aspiration pneumonia, bronchopneumonia, lobar pneumonia, virus pneumonia, atypical pneumonia, tuberculous pneumonia, pulmonary tuberculosis, fungus infection, pulmonary metastasis.

Severe community-acquired pneumonia. Epidemiology and prognostic factors.

Over a period of 4 consecutive yr, 92 nonimmunosuppressed patients with critical acute respiratory failure caused by severe community-acquired pneumonia were admitted to the respiratory intensive care unit (RICU) of a general hospital and mortality was associated with anticipated death within 4 to 5 yr, inadequate antibiotic treatment before RICU admission, mechanical ventilation requirements, use of PEEP, FIO2 greater than 0.6.

Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia*

It is indicated that aspiration pneumonitis renders the host more susceptible to respiratory tract infection with K. pneumoniae, concurrently priming the lung for an exaggerated inflammatory response; and that although tumor necrosis factor-α plays a major role in the host response to primary infection, it does not affect lung inflammation or defense after aspiration pneum onitis.