Pulmonary artery pressure measurement during exercise testing in patients with suspected pulmonary hypertension.

@article{Raeside2000PulmonaryAP,
  title={Pulmonary artery pressure measurement during exercise testing in patients with suspected pulmonary hypertension.},
  author={David Raeside and A A Smith and A Brown and K. R. Patel and Rajneesh Madhok and John G.F. Cleland and Andrew J Peacock},
  journal={The European respiratory journal},
  year={2000},
  volume={16 2},
  pages={
          282-7
        }
}
It is recognized that exercise produces abnormally large increases in pulmonary artery pressure in patients with pulmonary vascular disease as a consequence of a variety of disorders, but the relationship between pressure and cardiopulmonary exercise performance is poorly understood. This lack of understanding is due (in part) to difficulty making measurements of pulmonary haemodynamics using conventional fluid filled catheters. This article seeks to improve understanding by comparing variables… 
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An overview of the history of CPET is provided, how measurements are obtained and interpreted are described, and its use in diagnosis and monitoring of pulmonary hypertensive diseases including exercise-induced pulmonary hypertension and pulmonary hypertension associated heart and lung disease is discussed.
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Elevated pulmonary artery pressure on exercise can be associated with hemodynamic and ventilatory abnormalities typical of PAH, along with impaired exercise capacity and reduced QOL.
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    Advances in pulmonary hypertension
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The potential clinical utility of identifying “ normal” and “abnormal” pulmonary vascular response patterns to exercise in patients aged ≤50 yrs is discussed and the clinical significance of a hypertensive P pa response to exercise is currently uncertain.
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Exercise-induced PAH is an early, mild, and clinically relevant phase of the PAH spectrum, and the takeoff pattern was present in nearly all normals.
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The term “exercise pulmonary hypertension” may be the most adequate to describe an abnormal pulmonary haemodynamic response characterised by an excessive pulmonary arterial pressure (PAP) increase in relation to flow during exercise.
Reduced exercise capacity and stress-induced pulmonary hypertension in patients with scleroderma.
TLDR
Measurement of PASP during exercise may prove to be a useful tool for the identification of future resting PHTN, and is linearly related to exercise time and maximum workload achieved.
The relationship between the components of pulmonary artery pressure remains constant under all conditions in both health and disease.
TLDR
SPAP, MPAP, and DPAP were strongly related, and these relationships were maintained under varying conditions, and this finding will allow comparison between invasive and noninvasive descriptions of pulmonary hemodynamics found in the literature.
Cardiopulmonary exercise testing in the assessment of pulmonary hypertension
TLDR
The pathophysiology of PAH and secondary PH and its impact on cardiac function is discussed, the clinical presentation of patients with elevated pulmonary pressures is reviewed, a case for the use of CPX as an integral assessment technique is outlined and clinical recommendations for CPX are provided.
Exercise limitations in various forms of pulmonary hypertension
TLDR
The contribution of PH in exercise limitations observed in sickle cell disease and patients idiopathic pulmonary fibrosis is assessed and the use of exercise testing as parameter of outcome is assessed.
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References

SHOWING 1-10 OF 24 REFERENCES
Pulmonary artery pressure variation in patients with connective tissue disease: 24 hour ambulatory pulmonary artery pressure monitoring
TLDR
Conventional methods of assessment of the pulmonary circulation based on single measurements in the supine position may underestimate the stresses faced by the right side of the circulation.
The pressure-flow response of the pulmonary circulation in patients with heart failure and pulmonary vascular disease.
TLDR
In the majority of patients, it was found that irrespective of whether the hypertension was arterial or venous in origin or etiology: the mean PAP-flow relationship was linear; pulmonary capillary wedge pressure was greater than or equal to the average closure pressure of the pulmonary vascular bed and could therefore be used as the downstream pressure in calculating pulmonary vascular resistance.
Cardiopulmonary function in patients with pulmonary hypertension.
TLDR
Evidence is given that tissue hypoxia may be implicated in the genesis of the mild hyperventilation seen in lung disease, and the variability offindings in the different conditions associated with pulmonary hypertension suggests that increased pulmonary arterial pressure has no effect on lungfunction.
Oxygen uptake kinetics in response to exercise in patients with pulmonary vascular disease.
  • K. Sietsema
  • Medicine
    The American review of respiratory disease
  • 1992
TLDR
VO2 kinetics improved in patients with pulmonary hypertension and two with pulmonary hypoperfusion caused by congenital heart disease, consistent with the concept that VO2 Kinetics may be limited by pulmonary hemodynamics in the presence of disease.
Pulmonary artery pressure changes during exercise and daily activities in chronic heart failure.
TLDR
Neither symptoms nor pulmonary artery pressure during maximal exercise is the same as during daily activities, which may restrict the value of maximal exercise tests in assessing patients with chronic heart failure.
Contribution of multiple inert gas elimination technique to pulmonary medicine--4. Gas exchange abnormalities in pulmonary vascular and cardiac disease.
TLDR
Different clinical situations causing pulmonary vascular disease where gas exchange can be evaluated using the multiple inert gas elimination technique (MIGET) are reviewed, and the response to structural abnormalities in the pulmonary arteries in patients with primary pulmonary hypertension or cirrhosis of the liver is summarised.
Captopril as treatment for patients with pulmonary hypertension. Problem of variability in assessing chronic drug treatment.
TLDR
It is concluded that captopril appears to be ineffective in causing a sustained reduction in the pulmonary artery pressure or pulmonary vascular resistance in patients with primary pulmonary hypertension and that these patients experience spontaneous variability in their pulmonary resistance from hour to hour.
...
1
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3
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