Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease.

  • W. MacNee
  • Published 2005 in Proceedings of the American Thoracic Society
An imbalance between oxidants and antioxidants is considered to play a role in the pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable evidence that an increased oxidative burden occurs in the lungs of patients with this disorder, and this may be involved in many of the pathogenic processes, such as direct injury to lung… (More)