Pulmonary amyloidosis in hematological disorders.

  title={Pulmonary amyloidosis in hematological disorders.},
  author={J. F. Cordier},
  journal={Seminars in respiratory and critical care medicine},
  volume={26 5},
  • J. F. Cordier
  • Published 2005 in
    Seminars in respiratory and critical care…
Amyloidosis is defined by tissue deposits of amyloid, a proteic substance with a characteristic spatial structure of beta-sheet fibrils assembled into bundles. This structure results in specific staining with Congo red dye, with green birefringence under polarized light microscope. AL amyloid forms from amyloidogenic immunoglobulins produced by clonal plasma cells. Pulmonary amyloidosis may be either part of systemic amyloidosis (primary amyloidosis or associated with myeloma) or organ-limited… CONTINUE READING

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