Pulmonary Physical Therapy Techniques to Enhance Survival in Amyotrophic Lateral Sclerosis: A Systematic Review

  title={Pulmonary Physical Therapy Techniques to Enhance Survival in Amyotrophic Lateral Sclerosis: A Systematic Review},
  author={Chelsea E Macpherson and Clare C Bassile},
  journal={Journal of Neurologic Physical Therapy},
Background and Purpose: Respiratory insufficiency is the primary cause of morbidity and mortality in individuals with amyotrophic lateral sclerosis (ALS). Although mechanical interventions are effective in prolonging survival through respiratory support, pulmonary physical therapy interventions are being investigated. The purpose of this systematic review was to examine the effectiveness of pulmonary physical therapy interventions across the progressive stages of ALS. Methods: Six databases… Expand
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  • S. Pinto, M. Swash, M. de Carvalho
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  • Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
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There was no clear positive or negative outcome of the respiratory exercise protocol proposed, but it is suggested that inspiratory exercise promotes a transient improvement in the respiratory subscore and in the maximal voluntary ventilation, peak expiratory flow, and sniff inspiratory pressure. Expand
Diaphragm Training in Amyotrophic Lateral Sclerosis
There was a nonsignificant trend toward a slower rate of decline in respiratory function in those subjects who mastered the diaphragm training technique, however, only half the subjects were able to successfully change their pattern of breathing. Expand
Breathing new life into treatment advances for respiratory failure in amyotrophic lateral sclerosis patients.
Methods to determine respiratory failure in ALS, mechanical invasive and noninvasive ventilation, telemetry, diaphragm pacing, cough aids and respiratory exercise are reviewed, after a brief overlook of respiratory insufficiency in ALS. Expand
A Systematic Review of the Effect of Moderate Intensity Exercise on Function and Disease Progression in Amyotrophic Lateral Sclerosis
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Evidence suggests that moderate exercise is not associated with adverse outcomes in persons with early-stage ALS, and can be safely adapted to abilities, interests, specific response to exercise, accessibility, and family support. Expand
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Exercise may be beneficial in ALS patients once Bipap is used to control peripheral and muscle oxygenation, and a slower clinical course and a significant difference in the slope of the RFT were observed in the treated group, suggesting that exercise may bebeneficial in ALS customers. Expand
Amyotrophic lateral sclerosis: prolongation of life by noninvasive respiratory AIDS.
It is concluded that up to continuous use of NPPV, along with MAC when needed, can permit prolonged survival and delay the need for tracheotomy for a significant minority of ALS patients by > 1 year. Expand
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