Pulmonary Manifestations among Patients with Primary Biliary Cirrhosis

  title={Pulmonary Manifestations among Patients with Primary Biliary Cirrhosis},
  author={Deniz Koksal and Aydin Seref Koksal and Ahmet O Gurakar},
  booktitle={Journal of clinical and translational hepatology},
Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic liver disease caused by diffuse inflammation, destruction and fibrosis of the intrahepatic bile ducts, ultimately leading to cirrhosis, portal hypertension and liver failure. The pathogenesis of PBC is incompletely understood, but current data suggest roles for genetic susceptibility and environmental factors. PBC is often thought of as an organ-specific autoimmune disease, which mainly targets the liver; however, lung tissue… CONTINUE READING