Pulling direction as a reaction coordinate for the mechanical unfolding of single molecules.

@article{Best2008PullingDA,
  title={Pulling direction as a reaction coordinate for the mechanical unfolding of single molecules.},
  author={Robert B. Best and Emanuele Paci and Gerhard Hummer and Olga K. Dudko},
  journal={The journal of physical chemistry. B},
  year={2008},
  volume={112 19},
  pages={5968-76}
}
The folding and unfolding kinetics of single molecules, such as proteins or nucleic acids, can be explored by mechanical pulling experiments. Determining intrinsic kinetic information, at zero stretching force, usually requires an extrapolation by fitting a theoretical model. Here, we apply a recent theoretical approach describing molecular rupture in the… CONTINUE READING