Puerarin accelerates neural regeneration after sciatic nerve injury

  title={Puerarin accelerates neural regeneration after sciatic nerve injury},
  author={Minfei Wu and Guanjie Zhao and Xiaoyu Yang and Chuangang Peng and Jianwu Zhao and Jun Liu and Rui Li and Zhongli Gao},
  booktitle={Neural regeneration research},
Puerarin is a natural isoflavone isolated from plants of the genus Pueraria and functions as a protector against cerebral ischemia. We hypothesized that puerarin can be involved in the repair of peripheral nerve injuries. To test this hypothesis, doses of 10, 5, or 2.5 mg/kg per day puerarin (8-(β-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) were injected intraperitoneally into mouse models of sciatic nerve injury. Puerarin at the middle and high doses significantly up… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 20 references

Protective role of puerarin against cerebral ischemia and its pharmacological mechanism

Zhongguo Linchuang Yiyao Yanjiu Zazhi • 2007
View 2 Excerpts

Trip - tolide upregulates NGF synthesis in rat astrocyte cultures

GZ Yang
Neurochem Res • 2007