Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway

@inproceedings{Liu2013PuerarinSA,
  title={Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway},
  author={Ling-juan Liu and Li-qun Liu and Tao Bo and Shi-jun Li and Zhen An Zhu and Rong-rong Cui and Ding-an Mao},
  booktitle={International journal of endocrinology},
  year={2013}
}
Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts (hOBs) apoptosis is still unclear. In this study, we detected the function of puerarin on serum-free-induced cell apoptosis using ELISA and TUNEL arrays and then found that the… CONTINUE READING