• DOI:10.1016/0140-6736(91)90201-Y
Corpus ID: 36570135

Publication bias in clinical research

@article{Easterbrook1991PublicationBI,
  title={Publication bias in clinical research},
  author={P. Easterbrook and R. Gopalan and J. Berlin and D. R. Matthews},
  journal={The Lancet},
  year={1991},
  volume={337},
  pages={867-872}
}

P. Easterbrook, R. Gopalan, +1 author D. R. Matthews

Published 1991

Medicine

The Lancet

In a retrospective survey, 487 research projects approved by the Central Oxford Research Ethics Committee between 1984 and 1987, were studied for evidence of publication bias. As of May, 1990, 285 of the studies had been analysed by the investigators, and 52% of these had been published. Studies with statistically significant results were more likely to be published than those finding no difference between the study groups (adjusted odds ratio [OR] 2.32; 95% confidence interval [Cl] 1.25-4.28… CONTINUE READING

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