Publication bias and dissemination of clinical research.

  title={Publication bias and dissemination of clinical research.},
  author={Colin B. Begg and Jesse A Berlin},
  journal={Journal of the National Cancer Institute},
  volume={81 2},
Publication bias is a widely recognized phenomenon that occurs because of the influence of study results on the chances of publication. Usually, studies with positive results are more likely to be published than studies with negative results, which leads to a preponderance of false-positive results in the literature. Empiric studies have demonstrated that the induced bias is large and can have a serious impact on meta-analyses, in which data from several studies are aggregated, as well as on… CONTINUE READING


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