Public health interventions and epidemic intensity during the 1918 influenza pandemic

  title={Public health interventions and epidemic intensity during the 1918 influenza pandemic},
  author={Richard J. Hatchett and Carter E. Mecher and Marc Lipsitch},
  journal={Proceedings of the National Academy of Sciences},
  pages={7582 - 7587}
Nonpharmaceutical interventions (NPIs) intended to reduce infectious contacts between persons form an integral part of plans to mitigate the impact of the next influenza pandemic. Although the potential benefits of NPIs are supported by mathematical models, the historical evidence for the impact of such interventions in past pandemics has not been systematically examined. We obtained data on the timing of 19 classes of NPI in 17 U.S. cities during the 1918 pandemic and tested the hypothesis… 

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