Puberty in Subjects with Complete Androgen Insensitivity Syndrome

  title={Puberty in Subjects with Complete Androgen Insensitivity Syndrome},
  author={D. Papadimitriou and A. Linglart and Y. Morel and J. Chaussain},
  journal={Hormone Research in Paediatrics},
  pages={126 - 131}
  • D. Papadimitriou, A. Linglart, +1 author J. Chaussain
  • Published 2006
  • Medicine
  • Hormone Research in Paediatrics
  • Background: Androgen receptor defects affect the regulation of the gonadotropic axis. However, little is known about the timing of pubertal maturation in complete androgen insensitivity syndrome (CAIS). Aims: To evaluate growth, skeletal maturation and gonadotropin and sex steroid secretion in patients with CAIS and intact gonads at puberty. Methods: Clinical, auxological and hormonal evaluation of 9 patients with CAIS from birth up to 17 years of age, prior to gonadectomy, in a single… CONTINUE READING
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