Pteroylglutamic acid malabsorption in tropical sprue.

  title={Pteroylglutamic acid malabsorption in tropical sprue.},
  author={J J Corcino and G Coll and Frederick A. Klipstein},
  volume={45 4},
Pteroylglutamic acid (PGA) absorption was assessed in ten untreated tropical sprue (TS) and eight control subjects utilizing a marker perfusion technique. Physiologic concentrations of the vitamin (25 ng/ml) dissolved in iso-osmotic solutions containing either mannitol of glucose at a concentration of 55.6 mM were perfused on each subject on two consecutive days. A statistically significant difference in PGA absorption between TS and control subjects was obtained only when glucose was present… CONTINUE READING
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