Corpus ID: 189811507

Pterostilbene protects against traumatic spinal cord injury via inhibiting inflammation and oxidative stress

  title={Pterostilbene protects against traumatic spinal cord injury via inhibiting inflammation and oxidative stress},
  author={Yanhong Zhou and Zhaohui Hu and Ningning Li},
To evaluate the protective role of pterostilbene (PTE) on spinal cord injury (SCI) in SD rats. SD rats were randomly divided into three groups: sham group (laminectomy only); SCI group; SCI + PTE (15 mg/kg) group. SCI was induced using the modified weight-drop method (10 g × 4 cm) at the 10th thoracic vertebral (T10) level. PTE (15 mg/kg) or vehicle was administered twice by subarachnoid injection at lumbar 4 level twenty minutes and two hours after SCI. After 4 weeks of SCI, the injury part of… Expand

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