Corpus ID: 38030777

Pterostilbene protects against myocardial ischemia-reperfusion injury via activating eNOS in diabetic rats

  title={Pterostilbene protects against myocardial ischemia-reperfusion injury via activating eNOS in diabetic rats},
  author={Feng Liu and W Xiong and Jun Li and Junfen Wang and Hong Gao and Meishan Wu and Rui-Jing Liang and Linjie Luo and Keqi Chen and Shaohong Dong},
Diabetic patients are more susceptible to myocardial ischemic injury. Pterostilbene (Pte), an analog of resveratrol, exerts a cardioprotective effect. However, the protective effect of Pte against myocardial ischemia-reperfusion (MI/R) injury in diabetes remains unclear. Male SD rats were fed with high-fat diet and injected with streptozotocin once to induce diabetes. Rats were injected intraperitoneally with Pte before subjected to MI/R injury. The left ventricular function, infarct size… Expand

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