Pterocarpans phaseollin and neorautenol isolated from Erythrina addisoniae induce apoptotic cell death accompanied by inhibition of ERK phosphorylation.

@article{Wtjen2007PterocarpansPA,
  title={Pterocarpans phaseollin and neorautenol isolated from Erythrina addisoniae induce apoptotic cell death accompanied by inhibition of ERK phosphorylation.},
  author={W. W{\"a}tjen and A. Kulawik and A. Suckow-Schnitker and Y. Chovolou and R. Rohrig and S. Ruhl and A. Kampk{\"o}tter and J. Addae-Kyereme and C. Wright and C. Passreiter},
  journal={Toxicology},
  year={2007},
  volume={242 1-3},
  pages={
          71-9
        }
}
The genus Erythrina (Leguminosae), consisting of over 100 different species, is distributed in tropical regions. In traditional medicine, Erythrina species are used to treat cancer, but little is known about the anticancer mechanisms. From the stem bark of Erythrina addisoniae Hutch. & Dalziel, six prenylated pterocarpans were isolated and analysed for pharmacological activity: While calopocarpin, cristacarpin, orientanol c, and isoneorautenol showed only a weak or moderate toxicity in H4IIE… Expand
Flavonoids from Erythrina schliebenii.
Phaseolin Attenuates Lipopolysaccharide-Induced Inflammation in RAW 264.7 Cells and Zebrafish
Prenylated Pterocarpanes from Erythrina melanacantha
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