PtdIns(4,5)P2 Functions at the Cleavage Furrow during Cytokinesis

  title={PtdIns(4,5)P2 Functions at the Cleavage Furrow during Cytokinesis},
  author={Seth J. Field and Nikki Madson and Monica L. Kerr and Kenneth A.A. Galbraith and Caitlin E. Kennedy and Mamta Tahiliani and Andrew S. Wilkins and Lewis C. Cantley},
  journal={Current Biology},
Phosphoinositides play important roles in regulating the cytoskeleton and vesicle trafficking, potentially important processes at the cleavage furrow. However, it remains unclear which, if any, of the phosphoinositides play a role during cytokinesis. A systematic analysis to determine if any of the phosphoinositides might be present or of functional importance at the cleavage furrow has not been published. Several studies hint at a possible role for one or more phosphoinositides at the cleavage… CONTINUE READING
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