PtCl2-catalyzed tandem triple migration reaction toward (Z)-1,5-dien-2-yl esters.


A novel method for the selective synthesis of (Z)-1,5-dien-2-yl esters has been developed though Pt(II)-catalyzed tandem 1,2-acyl and 1,2-hydride migration, along with an allyl migration reaction of propargylic carboxylates with electronically unbiased internal alkynes. The unusual selectivity of 1,2-acyloxy migration was realized.

DOI: 10.1021/ol8015463

Cite this paper

@article{Ji2008PtCl2catalyzedTT, title={PtCl2-catalyzed tandem triple migration reaction toward (Z)-1,5-dien-2-yl esters.}, author={Ke-Gong Ji and Xing-zhong Shu and Jin Chen and Shu-chun Zhao and Zhao-Jing Zheng and Li Lu and Xueyuan Liu and Yong-Min Liang}, journal={Organic letters}, year={2008}, volume={10 17}, pages={3919-22} }