Psychosocial stress elevates blood pressure via an opioid dependent mechanism in normotensive rats.

@article{Szilagyi1991PsychosocialSE,
  title={Psychosocial stress elevates blood pressure via an opioid dependent mechanism in normotensive rats.},
  author={Jan Szilagyi},
  journal={Clinical and experimental hypertension. Part A, Theory and practice},
  year={1991},
  volume={13 8},
  pages={1383-94}
}
  • Jan Szilagyi
  • Published 1991 in
    Clinical and experimental hypertension. Part A…
Stress is an important risk factor in cardiovascular diseases, including hypertension. Endogenous opioids are known to be elevated in stress and in various models of hypertension with differing etiologies. Blockade of endogenous opioids with naloxone has been demonstrated to attenuate or reverse the elevation in blood pressure in both renovascular and spontaneous hypertension. In the current study, increased blood pressure was induced using a model of psychosocial stress. During the first week… CONTINUE READING