Psychosocial factors, sex differences, and atherosclerosis: lessons from animal models.

@article{Kaplan1996PsychosocialFS,
  title={Psychosocial factors, sex differences, and atherosclerosis: lessons from animal models.},
  author={Jay R. Kaplan and Michael Roy Adams and Thomas B. Clarkson and Stephen B. Manuck and Carol A. Shively and James Koudy Williams},
  journal={Psychosomatic medicine},
  year={1996},
  volume={58 6},
  pages={
          598-611
        }
}
OBJECTIVE Premenopausal women, compared with men, are relatively spared from coronary heart disease and the underlying atherosclerosis. Our purpose has been to elucidate the reason for this difference and to explore the role of behavioral factors in this phenomenon. METHODS Studies employed socially housed cynomolgus macaques (Macaca fascicularis) fed an atherogenic diet and subjected to behavioral observations. Ovariectomy, with or without hormone replacement, was used to test specific… CONTINUE READING

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