Psychosocial determinants of irritable bowel syndrome.

  title={Psychosocial determinants of irritable bowel syndrome.},
  author={Teodora Surdea-Blaga and Adriana S. Baban and Dan Lucian Dumitraşcu},
  journal={World journal of gastroenterology},
  volume={18 7},
From a pure motor disorder of the bowel, in the past few years, irritable bowel syndrome (IBS) has become a multifactorial disease that implies visceral hypersensitivity, alterations at the level of nervous and humoral communications between the enteric nervous system and the central nervous system, alteration of the gut microflora, an increased intestinal permeability and minimum intestinal inflammation. Psychological and social factors can interfere with the communication between the central… CONTINUE READING
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