Psychosis proneness and ADHD in young relatives of schizophrenia patients

  title={Psychosis proneness and ADHD in young relatives of schizophrenia patients},
  author={Matcheri S. Keshavan and Mandayam Sujata and Akhil Mehra and Debra M. Montrose and John A. Sweeney},
  journal={Schizophrenia Research},

Cognitive deficits in early-onset schizophrenia spectrum patients and their non-psychotic siblings: A comparison with ADHD

Delusion-proneness displays comorbidity with traits of autistic-spectrum disorders and ADHD

The findings support the idea that when investigating psychosis-proneness it is crucial to also take ADHD- and ASD-tendencies into account, in order to conclude that the reported results in a given study are specific to psychosis- proneness.

Shared and Nonshared Symptoms in Youth-Onset Psychosis and ADHD

Results suggested that academic, externalizing, and attention problems reflect symptoms shared between the disorders, whereas internalizing, social and thought problems reflect factors that differ between disorders.

Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder

The findings suggest that the co-occurrence of ADHD and bipolar disorder as well as ADHD and schizophrenia is due to shared genetic factors, rather than representing completely aetiologically distinct subsyndromes.

Attention Deficit Hyperactivity Disorder Symptoms and Psychosis in 22q11.2 Deletion Syndrome

The findings support a potentially important role of ADHD inattention symptoms in psychosis in 22q11.2DS and in other groups at risk for psychosis but without the deletion.



Characteristics of patients with schizophrenia successive to childhood attention deficit hyperactivity disorder (ADHD).

It is indicated that schizophrenia subsequent to childhood ADHD has a poor prognosis as compared to schizophrenic patients with a history of childhood attention deficit hyperactivity disorder.

Impaired attention, genetics, and the pathophysiology of schizophrenia.

It is concluded that the CPT is a cost-effective measure of the attentional deficit commonly found in affected schizophrenia subjects and those at risk for the disorder, and is therefore a potentially valuable screening device for preventive intervention programs.

Behavioral precursors of schizophrenia spectrum. A prospective study.

It is indicated that signs of defective emotional contact and formal thought disorder are important for the psychopathology of schizophrenia and the premorbid similarity of borderline schizophrenia and schizophrenia suggests a basic relationship between these two disorders.

Attention-deficit hyperactivity disorder and comorbid psychosis: a review and two clinical presentations.

It is suggested that further attention be given to the evaluation, treatment, and eventual classification of a potentially distinct patient group with ADHD and atypical psychotic episodes.

Attention, memory, and motor skills as childhood predictors of schizophrenia-related psychoses: the New York High-Risk Project.

OBJECTIVE Childhood neurobehavioral deficits in offspring of schizophrenic, affectively ill, and psychiatrically normal parents were evaluated as predictors of schizophrenia-related psychoses in

Adult psychiatric status of hyperactive boys grown up.

It is strongly suggested that children with ADHD are at significantly higher risk for a specific negative course marked by antisocial and substance-related disorders.

Putatively psychosis-prone subjects 10 years later.

The predictive validities of several indicators of psychosis proneness were evaluated in a 10-year longitudinal study and high scorers on the Perceptual Aberration Scale, Magical Ideation Scale, or both exceeded control subjects on psychoses, psychotic relatives, schizotypal symptoms, and psychoticlike experiences at follow up.