Psychosis or Obsessions? Clozapine Associated with Worsening Obsessive-Compulsive Symptoms

@inproceedings{Leung2016PsychosisOO,
  title={Psychosis or Obsessions? Clozapine Associated with Worsening Obsessive-Compulsive Symptoms},
  author={Jonathan G Leung and Brian A Palmer},
  booktitle={Case reports in psychiatry},
  year={2016}
}
One underrecognized adverse event of clozapine is the emergence or worsening of obsessive-compulsive symptoms (OCS). OCS, particularly violent thoughts, can be inaccurately described as psychosis and result in a misdiagnosis. We report a case of a 42-year-old man, initially diagnosed with schizoaffective, who was placed on clozapine for the management of "violent delusions." However, clozapine led to a worsening of these violent thoughts resulting in suicidal ideation and hospitalization. After… CONTINUE READING
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