Psychosis in advanced Parkinson's disease

@article{Zoldan1995PsychosisIA,
  title={Psychosis in advanced Parkinson's disease},
  author={Joseph Zoldan and G. Friedberg and Miron Livneh and Eldad Melamed},
  journal={Neurology},
  year={1995},
  volume={45},
  pages={1305 - 1308}
}
Psychosis, linked to chronic levodopa and other antiparkinsonian drug treatments, is a common and incapacitating complication of advanced Parkinson's disease (PD). The psychosis may be due, in part, to overstimulation of central serotonergic (5-HT) receptors. We treated 16 PD patients who had psychosis of 6 to 60 months' duration with the 5-HT3 receptor antagonist ondansetron (12 to 24 mg daily) in an open-label, short-term (4 to 8 weeks) trial. There was marked to moderate improvement (p < 0… 
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