Psychophysical and EEG responses to repeated experimental muscle pain in humans: pain intensity encodes EEG activity.

@article{Chang2003PsychophysicalAE,
  title={Psychophysical and EEG responses to repeated experimental muscle pain in humans: pain intensity encodes EEG activity.},
  author={Peng-fei Chang and Lars Arendt-Nielsen and Thomas Graven-Nielsen and Andrew C. N. Chen},
  journal={Brain research bulletin},
  year={2003},
  volume={59 6},
  pages={533-43}
}
Clinical pain is often characterized by repetitive and persistent occurrence in deep structures, but few studies investigated repetitive tonic pain in humans. To determine cerebral responses to repetitive tonic pain, psychophysical responses, and electroencephalographic (EEG) activation to five trials of repeated tonic muscle pain induced by hypertonic saline were examined and analyzed in 13 male subjects. The study was composed of two experimental sessions performed in separate days. Five… CONTINUE READING

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